Synthesis of β-C-galactosyl D- and L-alanines.
نویسندگان
چکیده
Synthesis of β-C-D-galactosyl D- and L-alanines is carried out via a highly stereoselective Grignard reaction of glycosyl iodides, Sharpless dihydroxylation and S(N)2 displacement of the corresponding mesylate or tosylate. Alternatively, attempted triflation of the intermediate alcohols triggers a stereoselective debenzylative cyclization leading to interesting bicyclic trans-fused compounds.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 10 40 شماره
صفحات -
تاریخ انتشار 2012